Biomarkers and precision medicine in genitourinary cancer

Research in this line seeks to develop tools that allow a more precise characterisation of the disease and better patient stratification.

To this end, we study tissue, blood and urine biomarkers with potential diagnostic, prognostic and predictive value, and integrate multi-omics approaches, advanced molecular analyses, artificial intelligence and imaging techniques to obtain a comprehensive view of tumour biology.

We also develop predictive models that support clinical decision-making and individualised treatment selection. This line promotes the adoption of innovative technologies in clinical practice, fostering more precise, efficient and patient-centred medicine.

The ultimate goal is to accelerate the translation of biological findings into clinical applications that improve health outcomes and optimise therapeutic management.

Projects and studies in this line

Project / studyTypeCancer typeSponsor / fundingPI
PrognoUroTaxinEvaluating the role of autotaxin as a prognostic factor in bladder cancerCNS2022-135994Research projectBladderAgencia Estatal de InvestigaciónElisa Matas Rico
MOLCARUTUCComprehensive genomic characterisation of upper urinary tract urothelial carcinoma and paired bladder recurrencesAC18/00021Research projectUpper urinary tract BladderInstituto de Salud Carlos III (acción complementaria internacional)
Development of diagnostic tools and biomarkers in collaboration with Mirnax BiosensRTC-2017-6501-1Research projectAgencia Estatal de Investigación (Retos-Colaboración)
BRECISEBiomarker Research and Evaluation for Clinical Implementation and Supporting Systems Enhancement101194784Research projectProstateUnión Europea · Horizonte Europa
SWALU23Development and validation of an automated system for prediction, diagnosis and early analysis of lower urinary tract disorders using signal processing and artificial intelligence on a smartwatchCPP2022-010045Research projectOtherAgencia Estatal de InvestigaciónBernardo Herrera Imbroda
Clinical, radiological and genetic evaluation of patients with metastatic hormone-sensitive prostate cancer treated with new-generation antiandrogensAEU21-001 · CPC21065Research projectProstateAsociación Española de UrologíaElisa Matas Rico
CAPTURETreatment patterns and outcomes in metastatic prostate cancer with and without somatic or germline homologous recombination repair gene alterationsObservationalProstate
PROVIDENCEPrediction of metastatic relapse in intermediate/high-risk localised prostate cancer from staging images and clinical variablesObservationalProstate
PROCUREPROCURE biomarker platform: PROREPAIR-B, PROSENZA, PROSTAC and PROSABI prospective studies in advanced prostate cancerObservationalProstate
HOPE-ProstateFeasibility and impact of liquid biopsy-based genomic profiling on treatment decisions in metastatic prostate cancer in SpainObservationalProstate
BLADIMIRNon-invasive tool for bladder cancer diagnosis and monitoring based on detection of miRNA in urineObservationalBladder